A 'VERSION' of you could live forever. Long after the biological original has gone to dust.
If you can take a high enough resolution 3D image of your central nervous system, and process that down to the core logical functionality, and build an emulator to run that simulation. All senses are inputs. All motor activity are outputs. And with version control and 'undo' on your virtual mind, interfacing it, modifying it, etc. becomes a trivial exercise. Ultra-high resolution senses. 'Psychic' powers. Direct mind-machine interfaces of any kind become child's play. Fix your little psychological 'hang-ups', directly, if you like. Live a thousand years in a day, or a day over a thousand years.
A perfect virtual you that never succumbs to entropy, because you're not made of sticky, gooey, biological matter. You're information.
Got killed in a rent-a-bod? Not a problem! Even if it was completely annihilated, computer brain blown to bits, you lost all the time since you jumped into that body, but wake up remembering everything up to that moment. Most likely the computer wouldn't be damaged, and you could be recovered and uplinked back to the main world. If some kind of a black box survived, you could play back the day up until you 'died', and basically recover the lost time, too.
Then as long as there was the computer, and energy to run the computer that ran your simulation (networked with other virtualized minds, in a virtual environment), you could live 'forever' in a land of plenty.
And the virtual worlds could certainly outlast 'real' worlds. A star orbiting metal can with solar panels and some antennae could keep such a world going long after a star went past its red giant phase. Long after all worlds around it are charred rocks. And the satellites could take a little nap and be boosted to other stars. Even if it took centuries to make the trip, the minds within would not be damaged. Or simply broadcast its citizens and their worlds to other, fresh, new satellites, around other, fresh, new stars. Even back them up, in case something happens. You could literally go on the trip and stay home, too. Or wait until the craft arrives and uplink to it, then.
Interstellar travel becomes a cakewalk. Speed of light travel becomes simple. Rent and inhabit bodies to do things in the 'real world'. Be perfect. Eat your cake, have it, eat it again. Never get fat, unless you want to be. Be whatever shape you want to be. Be whatever you want to be. Live in wonderland. Play in virtual worlds as yourself. Or selectively 'forget' and roleplay ultra-deeply in a game that lasts decades. Or reset your mind and spawn new versions of yourself. Be an engineer AND an artist. Go to school, forever learning, and never forgetting... unless you want to.
Got an Edison? An Einstein? Spawn a hundred of 'em. Faster, smaller, more efficient machines all the time. Filling the universe with virtual worlds and factories making more virtual worlds and more factories, would be pretty straight-forward, compared to colonizing worlds with biological people. And you could orbit a LOT of virtual world running computers around just ONE star. A billion earths with trillions of immortal people, around each star.
The universe is pretty darned big, and there are more than a few billion years' worth of generations of stars to get energy from, which gives plenty of time to come up with annihilation reactors and other energy sources to make matter into energy to continue running the systems long after the universe is a dark, cold, near vacuum with a few singularities scattered about.
Long, long, long after anything biological went extinct.
Seeding the void, patiently waiting a trillion years for more 'big bangs' to happen becomes a possibility, too.
A trillion-trillion-trillion immortal worlds and their industrial counterparts, sleeping, waiting.
Or perhaps doing something about it. Or running on interfaces bridging dimensions.